解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:OBJECTIVE:To test an educational intervention promoting the purchase of spectacles among Chinese children. DESIGN:Randomized, controlled trial. PARTICIPANTS:Children in years 1 and 2 of all 20 junior and senior high schools (ages 12-17 years) in 3 rural townships in Guangdong, China. METHODS:Children underwent visua...
journal_title:Ophthalmology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ophtha.2011.06.016
更新日期:2011-12-01 00:00:00
abstract:PURPOSE:To characterize the phenotype and investigate the associations of intraretinal crystalline deposits in a large cohort with type 2 idiopathic macular telangiectasia (MacTel). DESIGN:Case-control study. PARTICIPANTS:Patients with and without retinal crystals from the Macular Telangiectasia Project, an internati...
journal_title:Ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ophtha.2011.05.022
更新日期:2011-12-01 00:00:00
abstract:PURPOSE:To explain the mechanism for acquired enophthalmos after ventriculoperitoneal shunting (VPS). DESIGN:Case series and a case-control study. PARTICIPANTS AND CONTROLS:Four study patients with bilateral enophthalmos after VPS and 10 control subjects. METHODS:Case description of 4 study patients. Calculated orbi...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2011.04.031
更新日期:2011-11-01 00:00:00
abstract:PURPOSE:To evaluate the learning curve in Descemet's membrane endothelial keratoplasty (DMEK) in the management of corneal endothelial disorders. DESIGN:Retrospective, nonrandomized, clinical study at a tertiary referral center. PARTICIPANTS:We included 135 eyes of 118 patients with Fuchs' endothelial dystrophy. MET...
journal_title:Ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1016/j.ophtha.2011.03.037
更新日期:2011-11-01 00:00:00
abstract:PURPOSE:To describe the relationship between chronic systemic immune suppression and conjunctival squamous cell carcinoma (SCC). DESIGN:Retrospective interventional case series. PARTICIPANTS:Thirteen immunosuppressed patients with conjunctival SCC. METHODS:Surgical excision in all cases plus additional topical inter...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2011.04.001
更新日期:2011-11-01 00:00:00
abstract:PURPOSE:The mechanism of cupping reversal seen after lowering intraocular pressure (IOP) in pediatric glaucoma is unknown. Theories include forward movement of the lamina cribrosa or shrinkage of a stretched scleral canal. Our study aimed to quantify changes in optic disc size occurring in children who had undergone gl...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2011.02.041
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVE:To evaluate risk factors for astigmatism in a population-based sample of preschool children. DESIGN:Population-based cross-sectional study. PARTICIPANTS:Population-based samples of 9970 children ages 6 to 72 months from Los Angeles County, California, and Baltimore, Maryland. METHODS:A cross-sectional stud...
journal_title:Ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ophtha.2011.06.031
更新日期:2011-10-01 00:00:00
abstract:PURPOSE:To determine the factors that contribute to false-positive retinal nerve fiber layer (RNFL) color code results from spectral-domain optical coherence tomography (OCT). DESIGN:A prospective, cross-sectional study. PARTICIPANTS:This study included 149 eyes from 77 healthy participants. METHODS:Participants, wh...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2011.01.058
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:To characterize the abnormal head posture (AHP) in children with Down syndrome (DS). The study had 3 aims: to estimate the prevalence of AHP, to describe the distribution of different causes for AHP, and to evaluate the long-term outcomes of AHP in children with DS evaluated at the University of Iowa Hospitals ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2011.02.026
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:We examined changes in macular pigment optical density (MPOD) levels after cataract surgery and compared the MPOD between eyes with clear intraocular lenses (IOLs) and yellow-tinted IOLs. DESIGN:Prospective, comparative case series. PARTICIPANTS:The MPOD levels were measured in 480 eyes of 337 patients after ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2011.02.017
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVE:To analyze the topography of human eyes with pathologic myopia by high-resolution magnetic resonance imaging (MRI) with volume rendering of the acquired images. DESIGN:Observational case series. PARTICIPANTS:Eighty-six eyes of 44 patients with high myopia (refractive error ≥-8.00 diopters [D] or axial lengt...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2011.01.018
更新日期:2011-08-01 00:00:00
abstract:PURPOSE:To compare the vitreoretinal interface of the asymptomatic fellow eyes of patients with unilateral macular holes (MHs) with that of the asymptomatic fellow eyes of patients with other retinal diseases and with that of healthy eyes. DESIGN:Retrospective, observational cross-sectional study. PARTICIPANTS:This s...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2011.01.022
更新日期:2011-08-01 00:00:00
abstract:PURPOSE:We studied the 3-year efficacy and safety results of a 4-year study evaluating fluocinolone acetonide (FA) intravitreal implants in eyes with persistent or recurrent diabetic macular edema (DME). DESIGN:Prospective, evaluator-masked, controlled, multicenter clinical trial. PARTICIPANTS:We included 196 eyes wi...
journal_title:Ophthalmology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ophtha.2011.02.048
更新日期:2011-08-01 00:00:00
abstract:OBJECTIVE:To determine the prevalence of age-related macular degeneration (AMD) and to identify its risk factors in an Oklahoma Indian population. DESIGN:Cross-sectional study design. PARTICIPANTS:Included 1019 Oklahoma Indians who participated in baseline and second examinations of the Strong Heart Study. METHODS:R...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2010.11.007
更新日期:2011-07-01 00:00:00
abstract:PURPOSE:To investigate side effects seen with this formulation and to search for evidence of effectiveness after a single intravitreal injection of IBI-20089 in eyes with cystoid macular edema (CME) secondary to retinal vein occlusion. DESIGN:Prospective, phase 1 clinical trial. PARTICIPANTS:Ten patients with chronic...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2010.12.029
更新日期:2011-07-01 00:00:00
abstract:PURPOSE:To evaluate the clinical outcomes after implantation of the MyoRing (DIOPTEX GmBH, Linz, Austria) by means of femtosecond laser technology in eyes with corneal ectasia. DESIGN:Retrospective, consecutive, nonrandomized, case series. PARTICIPANTS:A total of 12 eyes of 11 patients with ages ranging from 17 to 50...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2010.12.012
更新日期:2011-07-01 00:00:00
abstract:PURPOSE:Herpes zoster has been associated with immune suppression, as has an increased risk of cancer. This population-based follow-up study aimed to investigate the risk of a subsequent cancer diagnosis after herpes zoster ophthalmicus (HZO). DESIGN:A retrospective cohort study. PARTICIPANTS AND CONTROLS:Retrospecti...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2010.10.008
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVE:Central retinal vein occlusion (CRVO) is a vision-threatening disease, primarily occurring among patients aged more than 60 years. Several risk factors, including arterial hypertension and diabetes mellitus, have been identified. Compression of the central retinal vein by an atherosclerotic retinal artery at ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2010.10.014
更新日期:2011-06-01 00:00:00
abstract:PURPOSE:To describe patient characteristics, classification, and onset of prethreshold retinopathy of prematurity (ROP), and ocular findings at 6 months corrected age in infants with birth weights <500 g who were enrolled in the Early Treatment for Retinopathy of Prematurity (ETROP) Study. DESIGN:Multicenter randomize...
journal_title:Ophthalmology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ophtha.2010.09.031
更新日期:2011-06-01 00:00:00
abstract:PURPOSE:To describe the prevalence and signs of early and late age-related macular degeneration (AMD) in an old cohort. DESIGN:Population-based cohort study. PARTICIPANTS:We included 5272 persons aged ≥66 years, randomly sampled from the Reykjavik area. METHODS:Fundus images were taken through dilated pupils using a...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2010.08.044
更新日期:2011-05-01 00:00:00
abstract:PURPOSE:To investigate the hypothesis that the excessive growth of the eye in myopia is associated with general growth and thus influenced by early life biological and social factors, and that these associations underlie recent secular trends of increasing prevalence and severity of myopia. DESIGN:Cohort study. PARTI...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2010.09.025
更新日期:2011-05-01 00:00:00
abstract:PURPOSE:To investigate the association in Japanese between posterior vitreous attachment and the pathologies of typical age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV), 2 major forms of exudative AMD. DESIGN:Retrospective observational case series. PARTICIPANTS:A total of 378 eyes f...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2010.09.001
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVE:Polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome is a rare disorder. This study investigated the types of ocular signs and symptoms in patients with POEMS and any systemic factors that may be associated with development of such ocular findings. DESIGN:Cas...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2010.08.013
更新日期:2011-04-01 00:00:00
abstract:OBJECTIVE:To compare the performance of the fast (256 A-scans in each scan circle) and the regular (512 A-scans in each scan circle) retinal nerve fiber layer (RNFL) scan protocols for detection of glaucoma progression using the Stratus optical coherence tomography (OCT) device (Carl Zeiss Meditec, Dublin, CA). DESIGN...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2010.08.014
更新日期:2011-04-01 00:00:00
abstract:OBJECTIVE:To describe presenting and corrected visual acuities after cataract surgery in a nationally representative sample of adults. Another objective was to describe refractive errors in operated eyes and to determine the optimal range of intraocular lens (IOL) powers for this population. DESIGN:Cross-sectional, po...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2010.08.025
更新日期:2011-04-01 00:00:00
abstract:PURPOSE:To describe the heritability and sibling risk for angle closure. DESIGN:Prospective clinical study. PARTICIPANTS:Probands with primary angle closure (PAC) and primary angle-closure glaucoma (PACG) and their first-degree relatives. METHODS:One hundred probands with PAC and PACG and their first-degree relative...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2010.06.043
更新日期:2011-03-01 00:00:00
abstract:PURPOSE:Autosomal-dominant optic atrophy (DOA) is one of the most common inherited optic neuropathies, and it is genetically heterogeneous, with mutations in both OPA1 and OPA3 known to cause disease. Approximately 60% of cases harbor OPA1 mutations, whereas OPA3 mutations have been reported in only 2 pedigrees with DO...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2010.07.029
更新日期:2011-03-01 00:00:00
abstract:OBJECTIVE:To evaluate the outcome of phototherapeutic keratectomy (PTK) treatment of epithelial basement membrane dystrophy (EBMD) patients and to examine clinical and morphologic signs of recurrent dystrophy. DESIGN:Cross-sectional, clinic-based study. PARTICIPANTS:Fifty-two eyes of 39 patients diagnosed with EBMD w...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2010.07.003
更新日期:2011-03-01 00:00:00
abstract:PURPOSE:To present the first 3 cases of Acanthamoeba keratitis (AK), unresponsive to medical treatment, that were successfully treated with a novel adjunctive therapy using ultraviolet light A (UVA) and riboflavin (B2). DESIGN:Interventional case series. PARTICIPANTS:Two patients with confirmed AK and 1 patient with ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2010.06.041
更新日期:2011-02-01 00:00:00
abstract:PURPOSE:To evaluate prognostic factors based on origin of conjunctival melanoma. DESIGN:Interventional case series. PARTICIPANTS:Three hundred eighty-two consecutive patients. METHODS:Retrospective chart review. MAIN OUTCOME MEASURES:Melanoma-related metastasis and death. RESULTS:The melanoma arose from primary ac...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2010.06.021
更新日期:2011-02-01 00:00:00
abstract:PURPOSE:To evaluate treatment of juxtapapillary choroidal melanoma with plaque radiotherapy and to investigate the role of supplemental transpupillary thermotherapy (TTT). DESIGN:Retrospective, comparative case series. PARTICIPANTS:We included 650 consecutive eyes with juxtapapillary choroidal melanoma within 1 mm of...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2010.06.007
更新日期:2011-02-01 00:00:00
abstract:TOPIC:Comparison of efficacy of intraocular pressure (IOP) reduction between 1- versus 2-site phacotrabeculectomy. CLINICAL RELEVANCE:The last systematic review concluded that there was weak evidence to suggest that 2-site phacotrabeculectomy provides 1- to 2-mmHg lower IOP than 1-site surgery. Since this study, there...
journal_title:Ophthalmology
pub_type: 杂志文章,meta分析
doi:10.1016/j.ophtha.2010.04.008
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVE:Newer treatment regimens for age-related macular degeneration have significantly affected traditional and non-traditional retinal services across all types of practice settings around the country as they seek to find a balance among delivering best patient care, keeping operating costs under control, and main...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2010.04.035
更新日期:2011-01-01 00:00:00
abstract:PURPOSE:To evaluate the long-term success rate of vitreoretinal surgery for severe cases of retinal capillary hemangiomas (RCHs) caused by von Hippel-Lindau (VHL) disease. DESIGN:Retrospective case series. PARTICIPANTS:Twenty-three eyes of 21 patients with severe exudative or tractional retinal detachment caused by R...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2010.04.031
更新日期:2011-01-01 00:00:00
abstract:PURPOSE:To investigate whether confluent drusen may be accompanied by fluid accumulation underneath the sensory retina and to determine if the detection of subretinal fluid on spectral-domain optical coherence tomography (OCT) in patients with coalescent drusen is indicative of choroidal neovascularization (CNV). DESI...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2010.04.017
更新日期:2011-01-01 00:00:00
abstract:PURPOSE:To evaluate the use of a peripheral stromal support to facilitate and improve the outcomes of Descemet's membrane endothelial keratoplasty (DMEK). DESIGN:Prospective case series. PARTICIPANTS:Ten patients with Fuchs' endothelial dystrophy. INTERVENTION:Pneumatic dissection was used to detach the central part...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2010.03.038
更新日期:2010-12-01 00:00:00
abstract:PURPOSE:To determine the independent, relative, and combined impact of reduced distance and near vision on the vision-specific quality of life (VS QOL) of adults in Timor-Leste. DESIGN:A population-based cross-sectional eye health survey was conducted in urban and rural areas in Timor-Leste. PARTICIPANTS:Participants...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2010.03.041
更新日期:2010-12-01 00:00:00
abstract:OBJECTIVE:To evaluate the responsiveness of 2 health-related quality-of-life (HRQOL) questionnaires, the Adult Strabismus-20 (AS-20) and National Eye Institute Visual Function Questionnaire-25 (VFQ-25), to changes in HRQOL after strabismus surgery. DESIGN:Cohort study. PARTICIPANTS:We included 106 adults (aged 18-84 ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2010.03.042
更新日期:2010-12-01 00:00:00
abstract:PURPOSE:To evaluate the visual outcome, number of injections, and direct medical cost of a "treat and extend" regimen (TER) in managing neovascular age-related macular degeneration (nAMD) with intravitreal ranibizumab. DESIGN:Retrospective, interventional, consecutive case series. PARTICIPANTS:Ninety-two eyes of 92 p...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2010.02.032
更新日期:2010-11-01 00:00:00
abstract:OBJECTIVE:To compare the reliability and the agreement in measuring central corneal thickness (CCT) using the following technologies: RTVue Fourier-domain optical coherence tomography (Optovue, Inc., Fremont, CA), Pentacam (Oculus, Inc., Wetzlar, Germany), and ultrasonic pachymetry (USP; Pocket-II; Quantel Medical, Inc...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2010.03.002
更新日期:2010-11-01 00:00:00